Those benefiting from Friday's action "are serving disproportionately long sentences compared to the sentences they would receive today under current law, policy, and practice", Biden said in a statement.
The move provides clemency relief to individuals who were sentenced based on discredited distinctions between crack and powder cocaine and outdated sentencing enhancements for drug crimes, according to the statement issued by the White House.
In December, Biden commuted sentences for 37 out of 40 federal inmates on death row, converting them to life in prison without parole, ahead of President-elect Donald Trump returning to the Oval Office on Monday (US time).
He also announced in December that he was pardoning 39 people convicted of non-violent crimes and commuting the sentences of almost 1500 others who were serving long prison terms.
Biden has faced criticism for pardoning his son, Hunter, who had pleaded guilty to tax violations and was convicted on firearms-related charges.
Defence lawyers and civil rights groups had ramped up efforts to highlight compelling cases and launched campaigns to help those they believed were wrongly convicted or were serving excessive terms for nonviolent offences.
Presidents typically order a round of pardons toward the end of their time in office.
Trump has promised to grant clemency to at least some of his supporters who stormed the US Capitol on January 6, 2021, in a failed bid to block Congress from certifying Biden's 2020 election victory.Â
